The 14th Annual HSCI Retreat was hosted at Harvard Medical School’s Joseph B. Martin Conference Center on Tuesday, May 21, 2019.

The event was chaired by Jon Hoggatt (Massachusetts General Hospital) and Vik Khurana (Brigham and Women's Hospital), with keynote speakers: Peter Marks, Director of the Center for Biologics Evaluation and Research at the FDA, and Beth Stevens, Associate Professor at Boston Children’s Hospital.

More details of this event available on the HSCI website here.

HSCI Scientific Retreat 2019 (Abstracts)

HSCI Retreat 2019 Abstracts

ALS-Implicated Pritein TDP-43 Sustains Levels of STMN2, a Mediator of Motor Neuron Growth and Regeneration
Joseph Klim,* Luis A. Williams, Francesco Limone, Irune Guerra San Juan, Brandi N. Davis-Dusenbery, Daniel A. Mordes, Aaron Burberry, Michael J. Steinbaugh, Kevin Eggan | View Abstract

Induced Pluripotent Stem Cells for Type 1 Diabetes In Vitro Modeling and Immunoprotection of β Cells
Nayara Leite,* Elad Sintov, and Doug Melton | View Abstract

Pre-Clinical Studies Toward Autologous Midbrain Dopamine Cell Therapy for Parkinson's Disease
Teresia Osborn,* Deepika Dinesh, Alyssa Moskites, Zach MacBain, Michele Moore, Oeystein Brekk, Arnar Astradsson, James Schumacher, Penny Hallett, Ole Isacson | View Abstract

Metabolic Crosstalk in the Bone Marrow Niche Drives Leukemia Chemoresistance
Nick van Gastel, * Jessica B. Spinelli, Amir Schajnovitz, Azeem Sharda, Konstantinos D. Kokkaliaris, Ninib Baryawno, Catherine Rhee, Toshihiko Oki, Charles Vidoudez, Eliane Grace, Sunia A. Trauger, Marcia C. Haigis, and David T. Scadden | View Abstract

Neural Crest Transcription Factors Induce Reactivation of Neural Crest Pprogenitor Cell Fate in Adult Zebrafish
Alicia McConnell,* Erika Weiskopf, and Leonard I. Zon | View Abstract

The Stem Cell Epigenome is Integral to the Pathogenesis of Psoriasis
Christine G. Lian,* Christine W. Yuan, Feng Li, Shuyun Xu, Tingjian Zu, Yvon Woappi, Catherine A. A. Lee, Phammela N. Abarzua, Michael Wells, Matt Ramsey, Natasha Y. Frank, Markus H. Frank, George F. Murphy  | View Abstract

Epigenome Dynamics Reveal Novel Mechanisms of Human Islet Differentiation and Maturation
Juan Alvarez,* Julie Donaghey, Jennifer H. R. Kenty, Niloofar Rasouli, Aharon Helman, Jocelyn Charlton, Juerg R. Straubhaar, Alexander Meissner, Douglas A. Melton | View Abstract

Submitted: Mar 13, 2020; Published online: Apr 15, 2020